San Marino’s Ministry of Finance and Budget, together with the Italian Embassy in San Marino, hosted a bilateral Italy–San Marino conference on anti-money laundering (AML) regulation and policy. The event aimed to take stock of the AML frameworks in each country and across the bilateral relationship, and to explore prospects for closer regulatory and operational cooperation. The conference brought together speakers from the Central Bank of the Republic of San Marino, the Italian Ministry of Finance, the European Commission, the Bank of Italy and the Guardia di Finanza. Discussion was framed by the European regulatory context, the need for effective domestic and cross-border coordination among supervisory authorities, and the supervisory implications of technological change, including new digital instruments and crypto-assets, which the organisers linked to ongoing convergence of rules and best practices. Further deepening of Italy–San Marino cooperation was positioned within the context of the Republic of San Marino’s Association Agreement with the European Union.