The Financial Action Task Force of Latin America (GAFILAT) held a preparatory meeting in Cusco, Peru from 13 to 15 May to support the launch of its Fifth Round of Mutual Evaluations and to address the near- and medium-term challenges expected under the new process. As part of Guatemala’s 2025 pro tempore presidency action plan, the meeting included a roundtable on anticipated implementation difficulties and identified good practices, with participation from invited delegates including the Financial Action Task Force (FATF) and MONEYVAL. The agenda also covered upcoming work on new requirements and the scope of changes introduced to Recommendation 4. In addition, participants discussed findings from a regional analysis of risk factors and facilitators of money laundering linked to human trafficking and reviewed results from a workshop on sector-specific red flags associated with money laundering arising from human trafficking.